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Independent production units for radiopharmaceutical companies

Who it's for

Everything you need to produce in Europe

Protherium offers independent production units to radiopharmaceutical companies preparing Phase II and Phase III clinical trials and pivoting to commercial operations. Our offer fully integrates the constraints of producing in a new country: regulatory requirements, staffing needs, production and logistics operations.
01

Production site network

Our first site in Gondreville, near Nancy, then a network across Europe.

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Dedicated units

Ready-to-use units dedicated to each client, supported by shared services.

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Radionuclide supply

Secure access to the radionuclides your product needs.

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Services

Design, equipment, tech transfer, production operation, regulatory affairs support and staff.

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Production site · Gondreville

Our first site,
near Nancy

Our first production site is under construction in Gondreville, a few kilometres from Nancy: a 7,100 m² platform designed exclusively for the production of radiopharmaceuticals.
DEC 2026Hot cells installed
at the Nancy site
APR 2027First two units
delivered to customers
Concrete block walls of the future production rooms
Building materials delivered to the Gondreville site
Excavation and formwork inside the Gondreville building
Worker inside the Gondreville building under construction
Interior of the Gondreville building before fit-out
Insulated ductwork and the technical mezzanine inside the Gondreville building
Scissor lift and forklift in the future production hall at Gondreville
Technicians positioning an air handling unit on the technical mezzanine
Steel mezzanine structure and ducting being installed in the Gondreville building
Gondreville site

A strategic crossroads in the heart of Europe

Airports

Metz-Nancy-Lorraine airport and Nancy-Essey airport nearby

Motorway connections

Direct links to Germany, Luxembourg, Belgium and Switzerland

Scientific ecosystem

Nancy University Hospital (CHRU), University of Lorraine, Lorraine Cancer Institute (ICL)

A supportive environment

Modern business parks, local support and healthcare expertise
Production units

A site organised in production units

The Gondreville site is organised into production units. Protherium operates its own unit for CMO/CDMO production and provides dedicated units to its clients, with shared services supporting the whole site.
  • Ready-to-use unit with hot cells installed
  • CMO production operation by Protherium
  • Sized for Phase II–III to commercial volumes
  • Full operational independence for the client

Up to six production units on site

M6Available unitView insideM5Available unitView insideM4Available unitView insideM1Protherium unit1,000 m²View insideM2Client unit1,000 m²View insideM3Available unitView inside

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Tap a unit to look inside

  • Protherium unit (CMO/CDMO)
  • Client units (reserved)
  • Available units
  • Available in April 2027
  • Up to six production units on site
Lemer Pax

Shielded production lines by Lemer Pax: get yours delivered and installed within 12 months.

Shielded production line, doors closed
Shielded production line · closed
Shielded production line, doors open
Shielded production line · open
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Supply of radionuclides

Secure access to radionuclides with on-site production

Isotope supply is one of the main factors limiting the broad adoption of radiopharmaceutical therapies. To secure supply for its customers, Protherium will produce lutetium‑177, terbium‑161, rhenium‑188 and astatine‑211 on site. Each unit is configured to operate a panel of radionuclides: hot cells, shielding and processes are adapted to the isotope your product needs, from beta to alpha emitters.
Beta · Auger / CE emittersAlpha emitters177Lu161Tb188Re90Y67Cu117mSn131I211At225Ac212Pb

On-site production of 177Lu, 161Tb, 188Re and 211At by Protherium, expected in 2027, subject to authorisation.

Services

Strong expertise to design and operate your unit

From the first plans to routine production, Protherium handles every step of your unit. We also integrate the constraints of producing in a new country, from regulations to teams and partners, so you can focus on your product.
01

Design and configuration

Design of the plans and configuration of your unit, adapted to your product, your process and local constraints.

02

Equipment

Supply and installation of hot cells, shielding and production equipment, along with radioprotection tools and supervision.

03

Tech transfer & qualification

Transfer of your process, then qualification and validation of equipment, methods and procedures.

04

Production operation

Day-to-day running of your production, from manufacturing to the delivery of your doses across Europe.

05

Regulatory affairs

Regulatory and administrative support to set up and run your production in Europe.

06

Specialised staffing

Recruitment of qualified staff, and training through the European School for Radiopharmaceutical Production (ESRPP).

Discover the ESRPP

An ecosystem from research to production

Protherium builds on the Nancy ecosystem, where research, clinical trials and GMP production of radiopharmaceuticals already work together.

English
contact@protherium.fr